Honey Bees and Malaria
You don't usually see "honey bees" and "malaria" in the same sentence.
That won't be the case, though, when Joseph DeRisi, a Howard Hughes Medical Institute investigator and professor and vice chair of the Department of Biochemistry and Biophysics, University of California, San Francisco, comes to the UC Davis campus to lecture on Monday, Jan. 9.
His presentation, "A Seminar in Two Acts: Honey Bees and Malaria," is from 10 to 11 a.m. in the main auditorium (Room 2005) of the Genome and Biomedical Sciences Facility.
The seminar, open to all interested persons, is sponsored by the Biological Networks Focus Group of the Genome Center. Host is Oliver Fiehn, professor in the Department of Molecular and Cellular Biology and the Genome Center.
DeRisi, a molecular biologist and biochemist, was named the recipient of a MacArthur Foundation Grant (also known as "the genius award") in 2004. In 2008, DeRisi won the Heinz Award for Technology, the Economy and Employment. Among his many accomplishments: he designed and programmed a groundbreaking tool for finding (and fighting) viruses -- the ViroChip, a DNA microarray that test for the presence of all known viruses in one step.
The DeRisi lab drew international attention last year with publications in Public Library of Science journals.
Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum (published in PLoS Biology, August 2011)
Temporal Analysis of the Honey Bee Microbiome Reveals Four Novel Viruses and Seasonal Prevalence of Known Viruses, Nosema, and Crithidia (published in PLoS One, June, 2011)
Among those working on the honey bee research and co-authoring the PLoS One paper was insect virus researcher Michelle Flenniken, a postdoctoral fellow in the Raul Andino lab at UC San Francisco and the recipient of the Häagen-Dazs Postdoctoral Fellowship in Honey Bee Biology at UC Davis.
Among DeRisi's collaborators on malaria research is UC Davis molecular biologist Shirley Luckhart, professor in the Department of Medical Microbiology and Immunology and an advisor in the Entomology Graduate Program.
DeRisi, who received his Ph.D. in biochemistry in 1999 from Stanford University, does amazing work.
He's a genius, to be sure.
Check out these links:
Joseph DeRisi Lab, UC San Francisco
Joe DeRisi: Biochemist (featured in TED ("Technology, Entertainment, Design" is a nonprofit devoted to Ideas Worth Spreading.)
Conversation with Joe DeRisi (New York Times)
Solving Medical Mysteries (YouTube)
Hunting the Next Killer Virus (YouTube)
Joseph DeRisi: Howard Hughes Medical Institute
Joseph DeRisi in Wikipedia
A honey bee heads toward a tower of jewels (Echium wildpretii). (Photo by Kathy Keatley Garvey)
The malaria mosquito, Anopheles gambiae. (Photo by Anthony Cornel, UC Davis)